3-Phosphoinositide-Dependent Kinase 1 Controls Breast Tumor Growth in a Kinase-Dependent but Akt-Independent Manner

3-Phosphoinositide-dependent protein kinase 1 (PDK1) is the pivotal element of the phosphatidylinositol 3 kinase (PI3K) signaling pathway because it phosphorylates Akt/PKB through interactions with phosphatidylinositol 3,4,5 phosphate. Recent data indicate that PDK1 is overexpressed in many breast c...

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Bibliografiska uppgifter
Huvudupphovsmän: Gagliardi, Paolo Armando, di Blasio, Laura, Orso, Francesca, Seano, Giorgio, Sessa, Roberto, Taverna, Daniela, Bussolino, Federico, Primo, Luca
Materialtyp: Artigo
Språk:Inglês
Publicerad: Neoplasia Press Inc. 2012
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431179/
https://ncbi.nlm.nih.gov/pubmed/22952425
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