PDK1-mediated activation of MRCKα regulates directional cell migration and lamellipodia retraction

Directional cell migration is of paramount importance in both physiological and pathological processes, such as development, wound healing, immune response, and cancer invasion. Here, we report that 3-phosphoinositide-dependent kinase 1 (PDK1) regulates epithelial directional migration and invasion...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gagliardi, Paolo Armando, di Blasio, Laura, Puliafito, Alberto, Seano, Giorgio, Sessa, Roberto, Chianale, Federica, Leung, Thomas, Bussolino, Federico, Primo, Luca
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2014
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121984/
https://ncbi.nlm.nih.gov/pubmed/25092657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201312090
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