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Chromosome breakage after G2 checkpoint release

DNA double-strand break (DSB) repair and checkpoint control represent distinct mechanisms to reduce chromosomal instability. Ataxia telangiectasia (A-T) cells have checkpoint arrest and DSB repair defects. We examine the efficiency and interplay of ATM's G2 checkpoint and repair functions. Arte...

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書誌詳細
主要な著者: Deckbar, Dorothee, Birraux, Julie, Krempler, Andrea, Tchouandong, Leopoldine, Beucher, Andrea, Walker, Sarah, Stiff, Tom, Jeggo, Penny, Löbrich, Markus
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064048/
https://ncbi.nlm.nih.gov/pubmed/17353355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200612047
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