Nephrotoxicity Induced by the R- and S-Enantiomers of N-(3,5-Dichlorophenyl)-2-hydroxysuccinimide (NDHS) and Their Sulfate Conjugates in Male Fischer 344 Rats

The agricultural fungicide N-(3,5-dichlorophenyl)succinimide (NDPS) induces nephrotoxicity characterized as polyuric renal failure and mediated via metabolites arising from oxidation of the succinimide ring. Recent findings have suggested that the stereochemical nature of NDPS metabolites may be an...

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Hlavní autoři: Rankin, Gary O., Anestis, Dianne K., Valentovic, Monica A., Sun, Hang, Triest, William E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063576/
https://ncbi.nlm.nih.gov/pubmed/17728037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2007.07.013
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