Regulation of O6-methylguanine-DNA methyltransferase by methionine in human tumour cells.

Methionine (MET)-dependent cell lines require MET to proliferate, and homocysteine (HCY) does not act as a substitute for this requirement. From six O6-methylguanine-DNA methyltransferase (MGMT)-efficient (mer+) cell lines tested, two medulloblastomas (Daoy and D-341) and a lung non-small-cell adeno...

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Autori principali: Kokkinakis, D. M., von Wronski, M. A., Vuong, T. H., Brent, T. P., Schold, S. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group|1 1997
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063394/
https://ncbi.nlm.nih.gov/pubmed/9062396
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