Characterization of the promoter region of the human O6-methylguanine-DNA methyltransferase gene.

O6-methylguanine-DNA methyltransferase (MGMT) is a ubiquitous protein responsible for repair of O6-alkylguanine, a mutagenic, carcinogenic and toxic lesion. To characterize the elements responsible for the regulation of the MGMT gene, a 2.6 kb Sstl fragment isolated from a genomic clone, was shown t...

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Библиографические подробности

Опубликовано в::	Nucleic Acids Res
Главные авторы:	Harris, L C, Potter, P M, Tano, K, Shiota, S, Mitra, S, Brent, T P
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Oxford University Press 1991
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329112/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1956775/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.22.6163
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