Characterization of the promoter region of the human O6-methylguanine-DNA methyltransferase gene.

O6-methylguanine-DNA methyltransferase (MGMT) is a ubiquitous protein responsible for repair of O6-alkylguanine, a mutagenic, carcinogenic and toxic lesion. To characterize the elements responsible for the regulation of the MGMT gene, a 2.6 kb Sstl fragment isolated from a genomic clone, was shown t...

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Bibliografische gegevens
Hoofdauteurs: Harris, L C, Potter, P M, Tano, K, Shiota, S, Mitra, S, Brent, T P
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1991
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC329112/
https://ncbi.nlm.nih.gov/pubmed/1956775
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