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Transgenic rescue from embryonic lethality and renal carcinogenesis in the Eker rat model by introduction of a wild-type Tsc2 gene

We recently reported that a germ-line insertion in the rat homologue of the human tuberous sclerosis gene (TSC2) gives rise to dominantly inherited cancer in the Eker rat model. In this study, we constructed transgenic Eker rats with introduction of a wild-type Tsc2 gene to ascertain whether suppres...

詳細記述

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書誌詳細
主要な著者: Kobayashi, Toshiyuki, Mitani, Hiroaki, Takahashi, Ri-ichi, Hirabayashi, Masumi, Ueda, Masatsugu, Tamura, Hiroshi, Hino, Okio
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences of the USA 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC20555/
https://ncbi.nlm.nih.gov/pubmed/9108092
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