Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor

Antzeko izenburuak

• A mutation in reverse transcriptase of bis(heteroaryl)piperazine-resistant human immunodeficiency virus type 1 that confers increased sensitivity to other nonnucleoside inhibitors.
  nork: Dueweke, T J, et al.
  Argitaratua: (1993)
• Spontaneous oxidation of bis(heteroaryl)methanes and bis(heteroaryl)carbinols to ketones
  nork: Luciano Forlani, et al.
  Argitaratua: (2004-01-01)
• 3′-Azido-3′-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes
  nork: Ren, Jingshan, et al.
  Argitaratua: (1998)
• Future of nonnucleoside reverse transcriptase inhibitors
  nork: Sluis-Cremer, Nicolas
  Argitaratua: (2018)
• A Mutation in the 3′ Region of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase (Y318F) Associated with Nonnucleoside Reverse Transcriptase Inhibitor Resistance
  nork: Harrigan, P. Richard, et al.
  Argitaratua: (2002)