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The molecular mechanism of the inhibition by licofelone of the biosynthesis of 5-lipoxygenase products
BACKGROUND AND PURPOSE: Licofelone is a dual inhibitor of the cyclooxygenase and 5-lipoxygenase (5-LO) pathway, and has been developed for the treatment of inflammatory diseases. Here, we investigated the molecular mechanisms underlying the inhibition by licofelone of the formation of 5-LO products....
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2050828/ https://ncbi.nlm.nih.gov/pubmed/17704828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707416 |
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