Transforming growth factor beta upregulates 5-lipoxygenase activity during myeloid cell maturation.

Por Steinhilber, D, Rådmark, O, Samuelsson, B
Publicado em 1993

Sequential induction of 5-lipoxygenase gene expression and activity in Mono Mac 6 cells by transforming growth factor beta and 1,25-dihydroxyvitamin D3.

Por Brungs, M, Rådmark, O, Samuelsson, B, Steinhilber, D
Publicado em 1995

Glutathione peroxidase-1 but not -4 is involved in the regulation of cellular 5-lipoxygenase activity in monocytic cells.

Por Straif, D, Werz, O, Kellner, R, Bahr, U, Steinhilber, D
Publicado em 2000

On the expression and regulation of 5-lipoxygenase in human lymphocytes.

Por Jakobsson, P J, Steinhilber, D, Odlander, B, Rådmark, O, Claesson, H E, Samuelsson, B
Publicado em 1992

5-Lipoxygenase inhibitors induce potent anti-proliferative and cytotoxic effects in human tumour cells independently of suppression of 5-lipoxygenase activity

Por Fischer, AS, Metzner, J, Steinbrink, SD, Ulrich, S, Angioni, C, Geisslinger, G, Steinhilber, D, Maier, TJ
Publicado em 2010

Inhibition of class I HDACs abrogates the dominant effect of MLL-AF4 by activation of wild-type MLL

Por Ahmad, K, Katryniok, C, Scholz, B, Merkens, J, Löscher, D, Marschalek, R, Steinhilber, D
Publicado no Oncogenesis (2014)

5-Lipoxygenase contributes to PPARγ activation in macrophages in response to apoptotic cells

Por von Knethen, A, Eifler, L, Kuchler, L, Heeg, A, Heide, H, Wittig, I, Maier, T, Steinhilber, D, Brüne, B
Publicado em 2012

2-(4-(Biphenyl-4-ylamino)-6-chloropyrimidin-2-ylthio)octanoic acid (HZ52) – a novel type of 5-lipoxygenase inhibitor with favourable molecular pharmacology and efficacy in vivo

Por Greiner, C, Hörnig, C, Rossi, A, Pergola, C, Zettl, H, Schubert-Zsilavecz, M, Steinhilber, D, Sautebin, L, Werz, O
Publicado em 2011

The molecular mechanism of the inhibition by licofelone of the biosynthesis of 5-lipoxygenase products

Por Fischer, L, Hornig, M, Pergola, C, Meindl, N, Franke, L, Tanrikulu, Y, Dodt, G, Schneider, G, Steinhilber, D, Werz, O
Publicado em 2007

A pirinixic acid derivative (LP105) inhibits murine 5-lipoxygenase activity and attenuates vascular remodelling in a murine model of aortic aneurysm

Por Revermann, M, Mieth, A, Popescu, L, Paulke, A, Wurglics, M, Pellowska, M, Fischer, AS, Steri, R, Maier, TJ, Schermuly, RT, Geisslinger, G, Schubert-Zsilavecz, M, Brandes, RP, Steinhilber, D
Publicado em 2011

Molecular pharmacological profile of a novel thiazolinone-based direct and selective 5-lipoxygenase inhibitor

Por Hofmann, B, Rödl, CB, Kahnt, AS, Maier, TJ, Michel, AA, Hoffmann, M, Rau, O, Awwad, K, Pellowska, M, Wurglics, M, Wacker, M, Živković, A, Fleming, I, Schubert-Zsilavecz, M, Stark, H, Schneider, G, Steinhilber, D
Publicado em 2012