On the inhibition of 5-lipoxygenase product formation by tryptanthrin: mechanistic studies and efficacy in vivo

Por Pergola, C, Jazzar, B, Rossi, A, Northoff, H, Hamburger, M, Sautebin, L, Werz, O
Publicado em 2012

The 5-lipoxygenase inhibitor, zileuton, suppresses prostaglandin biosynthesis by inhibition of arachidonic acid release in macrophages

Por Rossi, A, Pergola, C, Koeberle, A, Hoffmann, M, Dehm, F, Bramanti, P, Cuzzocrea, S, Werz, O, Sautebin, L
Publicado em 2010

2-(4-(Biphenyl-4-ylamino)-6-chloropyrimidin-2-ylthio)octanoic acid (HZ52) – a novel type of 5-lipoxygenase inhibitor with favourable molecular pharmacology and efficacy in vivo

Por Greiner, C, Hörnig, C, Rossi, A, Pergola, C, Zettl, H, Schubert-Zsilavecz, M, Steinhilber, D, Sautebin, L, Werz, O
Publicado em 2011

The molecular mechanism of the inhibition by licofelone of the biosynthesis of 5-lipoxygenase products

Por Fischer, L, Hornig, M, Pergola, C, Meindl, N, Franke, L, Tanrikulu, Y, Dodt, G, Schneider, G, Steinhilber, D, Werz, O
Publicado em 2007

The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)

Por Pergola, C, Gerstmeier, J, Mönch, B, Çalışkan, B, Luderer, S, Weinigel, C, Barz, D, Maczewsky, J, Pace, S, Rossi, A, Sautebin, L, Banoglu, E, Werz, O
Publicado em 2014

Elucidation of the molecular mechanism and the efficacy in vivo of a novel 1,4-benzoquinone that inhibits 5-lipoxygenase

Por Schaible, A M, Filosa, R, Temml, V, Krauth, V, Matteis, M, Peduto, A, Bruno, F, Luderer, S, Roviezzo, F, Di Mola, A, Rosa, M, D'Agostino, B, Weinigel, C, Barz, D, Koeberle, A, Pergola, C, Schuster, D, Werz, O
Publicado em 2014