New insights into human prostacyclin receptor structure and function through natural and synthetic mutations of transmembrane charged residues

BACKGROUND AND PURPOSE: The human prostacyclin receptor (hIP), a G-protein coupled receptor (GPCR) expressed mainly on platelets and vascular smooth muscle cells, plays important protective roles in the cardiovascular system. We hypothesized that significant insights could be gained into the structu...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Stitham, J, Arehart, E, Gleim, S R, Li, N, Douville, K, Hwa, J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2007
Aiheet:
Research Papers
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2050826/
https://ncbi.nlm.nih.gov/pubmed/17704830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707413
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