Comprehensive Biochemical Analysis of Rare Prostacyclin Receptor Variants: STUDY OF ASSOCIATION OF SIGNALING WITH CORONARY ARTERY OBSTRUCTION

Currently, pharmacogenetic studies are at an impasse as the low prevalence (<2%) of most variants hinder their pharmacogenetic analysis with population sizes often inadequate for sufficiently powered studies. Grouping rare mutations by functional phenotype rather than mutation site can potentiall...

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Hlavní autoři: Stitham, Jeremiah, Arehart, Eric, Elderon, Larkin, Gleim, Scott R., Douville, Karen, Kasza, Zsolt, Fetalvero, Kristina, MacKenzie, Todd, Robb, John, Martin, Kathleen A., Hwa, John
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044963/
https://ncbi.nlm.nih.gov/pubmed/21189259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.124933
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