Prostaglandin E(2) Suppresses Bacterial Killing in Alveolar Macrophages by Inhibiting NADPH Oxidase

Prostaglandin E(2) (PGE(2)) is a potent lipid mediator that effects changes in cell functions through ligation of four distinct G protein–coupled E prostanoid (EP) receptors (EP1–EP4). PGE(2) inhibits bacterial killing and reactive oxygen intermediate (ROI) production by alveolar macrophages (AMs),...

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Auteurs principaux: Serezani, Carlos H., Chung, Jooho, Ballinger, Megan N., Moore, Bethany B., Aronoff, David M., Peters-Golden, Marc
Format: Artigo
Langue:Inglês
Publié: American Thoracic Society 2007
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2048683/
https://ncbi.nlm.nih.gov/pubmed/17585108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0153OC
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