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Requirement of Helix P2.2 and Nucleotide G1 for Positioning the Cleavage Site and Cofactor of the glmS Ribozyme
The glmS ribozyme is a catalytic RNA that self-cleaves at its 5′-end in the presence of glucosamine-6-phosphate (GlcN6P). We present structures of the glmS ribozyme from Thermoanaerobacter tengcongensis that are bound with the cofactor GlcN6P or the inhibitor glucose-6-phosphate (Glc6P) at 1.7 Å and...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2048488/ https://ncbi.nlm.nih.gov/pubmed/17804015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.07.062 |
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