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Modulation of the Brd4/P-TEFb Interaction by the Human T-Lymphotropic Virus Type 1 Tax Protein

Positive transcription elongation factor (P-TEFb), which is composed of CDK9 and cyclin T1, plays an important role in cellular and viral gene expression. Our lab has recently demonstrated that P-TEFb is required for Tax transactivation of the viral long terminal repeat (LTR). P-TEFb is found in two...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cho, Won-Kyung, Zhou, Meisheng, Jang, Moon Kyoo, Huang, Keven, Jeong, Soo-Jin, Ozato, Keiko, Brady, John N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045532/
https://ncbi.nlm.nih.gov/pubmed/17686863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00408-07
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