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Human T-Lymphotropic Virus Type 1 Tax Protein Complexes with P-TEFb and Competes for Brd4 and 7SK snRNP/HEXIM1 Binding

Positive transcription elongation factor b (P-TEFb) plays an important role in stimulating RNA polymerase II elongation for viral and cellular gene expression. P-TEFb is found in cells in either an active, low-molecular-weight (LMW) form or an inactive, high-molecular-weight (HMW) form. We report he...

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Main Authors: Cho, Won-Kyung, Jang, Moon Kyoo, Huang, Keven, Pise-Masison, Cynthia A., Brady, John N.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004308/
https://ncbi.nlm.nih.gov/pubmed/20926576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00943-10
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