Bromodomain Protein Brd4 Regulates Human Immunodeficiency Virus Transcription through Phosphorylation of CDK9 at Threonine 29

Positive transcription elongation factor b (P-TEFb), composed of cyclin-dependent kinase 9 (CDK9) and cyclin T, is a global transcription factor for eukaryotic gene expression, as well as a key factor for human immunodeficiency virus (HIV) transcription elongation. P-TEFb phosphorylates the carboxyl...

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Main Authors: Zhou, Meisheng, Huang, Keven, Jung, Kyung-Jin, Cho, Won-Kyung, Klase, Zach, Kashanchi, Fatah, Pise-Masison, Cynthia A., Brady, John N.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612389/
https://ncbi.nlm.nih.gov/pubmed/18971272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01316-08
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