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In Transduced Cells, the U(S)3 Protein Kinase of Herpes Simplex Virus 1 Precludes Activation and Induction of Apoptosis by Transfected Procaspase 3

The U(S)3 protein kinase of herpes simplex virus 1 blocks apoptosis induced by replication-incompetent virus mutants, proapoptotic members of the Bcl-2 family of proteins, and by a variety of other agents that act at the premitochondrial level in the proapoptotic cascade. To define the role of U(S)3...

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Detalhes bibliográficos
Main Authors: Benetti, Luca, Roizman, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045497/
https://ncbi.nlm.nih.gov/pubmed/17634220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00820-07
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