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The U(S)3 Protein Kinase Blocks Apoptosis Induced by the d120 Mutant of Herpes Simplex Virus 1 at a Premitochondrial Stage

Earlier studies have shown that the d120 mutant of herpes simplex virus 1, which lacks both copies of the α4 gene, induces caspase-3-dependent apoptosis in HEp-2 cells. Apoptosis was also induced by the α4 rescuant but was blocked by the complementation of rescuant with a DNA fragment encoding the U...

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Autors principals: Munger, Joshua, Chee, Ana V., Roizman, Bernard
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC114261/
https://ncbi.nlm.nih.gov/pubmed/11356956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.12.5491-5497.2001
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