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Protein Kinase B/Akt Is Present in Activated Form throughout the Entire Replicative Cycle of ΔU(S)3 Mutant Virus but Only at Early Times after Infection with Wild-Type Herpes Simplex Virus 1
The product of the herpes simplex virus 1 (HSV-1) US3 gene is a multifunctional serine-threonine protein kinase that can block apoptosis induced by proapoptotic cellular proteins, exogenous agents, or replication-defective viruses. Earlier studies showed that the U(S)3 kinase activates and functiona...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1440418/ https://ncbi.nlm.nih.gov/pubmed/16537601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.7.3341-3348.2006 |
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