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Protein Kinase B/Akt Is Present in Activated Form throughout the Entire Replicative Cycle of ΔU(S)3 Mutant Virus but Only at Early Times after Infection with Wild-Type Herpes Simplex Virus 1

The product of the herpes simplex virus 1 (HSV-1) US3 gene is a multifunctional serine-threonine protein kinase that can block apoptosis induced by proapoptotic cellular proteins, exogenous agents, or replication-defective viruses. Earlier studies showed that the U(S)3 kinase activates and functiona...

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מידע ביבליוגרפי
Main Authors: Benetti, Luca, Roizman, Bernard
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440418/
https://ncbi.nlm.nih.gov/pubmed/16537601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.7.3341-3348.2006
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