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The Herpes Simplex Virus 1 U(S)3 Protein Kinase Blocks Caspase-Dependent Double Cleavage and Activation of the Proapoptotic Protein BAD

An earlier report showed that the U(S)3 protein kinase blocked the apoptosis induced by the herpes simplex virus 1 (HSV-1) d120 mutant at a premitochondrial stage. Further studies revealed that the kinase also blocks programmed cell death induced by the proapoptotic protein BAD. Here we report the e...

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Autori principali: Benetti, Luca, Munger, Joshua, Roizman, Bernard
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC155029/
https://ncbi.nlm.nih.gov/pubmed/12743316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.11.6567-6573.2003
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