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Processing of Open Reading Frame 1a Replicase Proteins nsp7 to nsp10 in Murine Hepatitis Virus Strain A59 Replication

Coronaviruses express open reading frame 1a (ORF1a) and ORF1b polyproteins from which 16 nonstructural proteins (nsp) are derived. The highly conserved region at the carboxy terminus of ORF1a is processed by the nsp5 proteinase (M(pro)) into mature products, including nsp7, nsp8, nsp9, and nsp10, pr...

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Detalles Bibliográficos
Main Authors: Deming, Damon J., Graham, Rachel L., Denison, Mark R., Baric, Ralph S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045455/
https://ncbi.nlm.nih.gov/pubmed/17634238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00017-07
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