MARKK, a Ste20-like kinase, activates the polarity-inducing kinase MARK/PAR-1
MARK, a kinase family related to PAR-1 involved in establishing cell polarity, phosphorylates microtubule-associated proteins (tau/MAP2/MAP4) at KXGS motifs, causes detachment from microtubules, and their disassembly. The sites are prominent in tau from Alzheimer’s disease brains. We studied the act...
保存先:
| 出版年: | EMBO J |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2003
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC204455/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14517247/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg447 |
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