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MARKK, a Ste20-like kinase, activates the polarity-inducing kinase MARK/PAR-1

MARK, a kinase family related to PAR-1 involved in establishing cell polarity, phosphorylates microtubule-associated proteins (tau/MAP2/MAP4) at KXGS motifs, causes detachment from microtubules, and their disassembly. The sites are prominent in tau from Alzheimer’s disease brains. We studied the act...

詳細記述

保存先:
書誌詳細
出版年:EMBO J
主要な著者: Timm, Thomas, Li, Xiao-Yu, Biernat, Jacek, Jiao, Jian, Mandelkow, Eckhard, Vandekerckhove, Joel, Mandelkow, Eva-Maria
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC204455/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14517247/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg447
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