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MARKK, a Ste20-like kinase, activates the polarity-inducing kinase MARK/PAR-1

MARK, a kinase family related to PAR-1 involved in establishing cell polarity, phosphorylates microtubule-associated proteins (tau/MAP2/MAP4) at KXGS motifs, causes detachment from microtubules, and their disassembly. The sites are prominent in tau from Alzheimer’s disease brains. We studied the act...

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Sonraí Bibleagrafaíochta
Main Authors: Timm, Thomas, Li, Xiao-Yu, Biernat, Jacek, Jiao, Jian, Mandelkow, Eckhard, Vandekerckhove, Joel, Mandelkow, Eva-Maria
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2003
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC204455/
https://ncbi.nlm.nih.gov/pubmed/14517247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg447
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