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MARKK, a Ste20-like kinase, activates the polarity-inducing kinase MARK/PAR-1
MARK, a kinase family related to PAR-1 involved in establishing cell polarity, phosphorylates microtubule-associated proteins (tau/MAP2/MAP4) at KXGS motifs, causes detachment from microtubules, and their disassembly. The sites are prominent in tau from Alzheimer’s disease brains. We studied the act...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC204455/ https://ncbi.nlm.nih.gov/pubmed/14517247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg447 |
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