MARKK, a Ste20-like kinase, activates the polarity-inducing kinase MARK/PAR-1

MARK, a kinase family related to PAR-1 involved in establishing cell polarity, phosphorylates microtubule-associated proteins (tau/MAP2/MAP4) at KXGS motifs, causes detachment from microtubules, and their disassembly. The sites are prominent in tau from Alzheimer’s disease brains. We studied the act...

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Detalles Bibliográficos

Publicado en:	EMBO J
Principais autores:	Timm, Thomas, Li, Xiao-Yu, Biernat, Jacek, Jiao, Jian, Mandelkow, Eckhard, Vandekerckhove, Joel, Mandelkow, Eva-Maria
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Publishing Group 2003
Assuntos:	Articles
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC204455/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14517247/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg447
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