MARKK, a Ste20-like kinase, activates the polarity-inducing kinase MARK/PAR-1

MARK, a kinase family related to PAR-1 involved in establishing cell polarity, phosphorylates microtubule-associated proteins (tau/MAP2/MAP4) at KXGS motifs, causes detachment from microtubules, and their disassembly. The sites are prominent in tau from Alzheimer’s disease brains. We studied the act...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Timm, Thomas, Li, Xiao-Yu, Biernat, Jacek, Jiao, Jian, Mandelkow, Eckhard, Vandekerckhove, Joel, Mandelkow, Eva-Maria
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2003
Fag:	Articles
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC204455/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14517247/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg447
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!