Attenuated Free Cholesterol Loading-induced Apoptosis but Preserved Phospholipid Composition of Peritoneal Macrophages from Mice That Do Not Express Group VIA Phospholipase A(2)

Previous studies suggest that group VIA phospholipase A(2) (iPLA(2)β) participates in endoplasmic reticulum (ER) stress-induced apoptosis, and mouse macrophages undergo ER stress and apoptosis upon free cholesterol loading (FCL). We recently generated iPLA(2)β-null mice, and here we demonstrate that...

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Detalhes bibliográficos
Main Authors: Bao, Shunzhong, Li, Yankun, Lei, Xiaoyong, Wohltmann, Mary, Jin, Wu, Bohrer, Alan, Semenkovich, Clay F., Ramanadham, Sasanka, Tabas, Ira, Turk, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2044506/
https://ncbi.nlm.nih.gov/pubmed/17627946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M701316200
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