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THE ONCOGENIC FUSION PROTEIN PAX3-FKHR HAS A GREATER POST-TRANSLATIONAL STABILITY RELATIVE TO PAX3 DURING EARLY MYOGENESIS

The childhood solid muscle tumor Alveolar Rhabdomyosarcoma (ARMS) is characterized by the t(2;13)(q35;q14) chromosomal translocation, which results in the fusion of two transcription factors important for myogenesis, Pax3 and FKHR (FOX01a). The effects of myogenic differentiation on the stability of...

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Bibliographic Details
Main Authors: Miller, Patrick J., Hollenbach, Andrew D.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043499/
https://ncbi.nlm.nih.gov/pubmed/17698292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2007.06.016
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