The Oncogenic Potential of the Pax3-FKHR Fusion Protein Requires the Pax3 Homeodomain Recognition Helix but Not the Pax3 Paired-Box DNA Binding Domain

The chimeric transcription factor Pax3-FKHR, produced by the t(2;13)(q35;q14) chromosomal translocation in alveolar rhabdomyosarcoma, consists of the two Pax3 DNA binding domains (paired box and homeodomain) fused to the C-terminal forkhead (FKHR) sequences that contain a potent transcriptional acti...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Lam, Paula Y. P., Sublett, Jack E., Hollenbach, Andrew D., Roussel, Martine F.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1999
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC83917/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9858583/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.1.594
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