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The Pax3-FKHR oncoprotein is unresponsive to the Pax3-associated repressor hDaxx.

The Pax3-FKHR fusion protein is present in alveolar rhabdomyosarcoma and results from the t(2;13) (q35;q14) chromosomal translocation. Its oncogenic activity is dependent on a combination of protein-DNA and protein-protein interactions mediated by the Pax3 homeodomain recognition helix. In this repo...

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Detalhes bibliográficos
Main Authors: Hollenbach, A D, Sublett, J E, McPherson, C J, Grosveld, G
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171447/
https://ncbi.nlm.nih.gov/pubmed/10393185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.13.3702
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