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Pax3-FKHR Knock-In Mice Show Developmental Aberrations but Do Not Develop Tumors
Alveolar rhabdomyosarcoma is a pediatric disease specified by the recurrent chromosome translocations t(2;13) and t(1;13). These translocations result in the formation of the PAX3-FKHR and PAX7-FKHR fusion genes, which are thought to play a causal role in the genesis of this disease. Although PAX3-F...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC139793/ https://ncbi.nlm.nih.gov/pubmed/12242297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.20.7204-7216.2002 |
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