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Pax3-FKHR Knock-In Mice Show Developmental Aberrations but Do Not Develop Tumors

Alveolar rhabdomyosarcoma is a pediatric disease specified by the recurrent chromosome translocations t(2;13) and t(1;13). These translocations result in the formation of the PAX3-FKHR and PAX7-FKHR fusion genes, which are thought to play a causal role in the genesis of this disease. Although PAX3-F...

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Detalhes bibliográficos
Main Authors: Lagutina, Irina, Conway, Simon J., Sublett, Jack, Grosveld, Gerard C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC139793/
https://ncbi.nlm.nih.gov/pubmed/12242297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.20.7204-7216.2002
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