Pax3-FKHR Knock-In Mice Show Developmental Aberrations but Do Not Develop Tumors

Alveolar rhabdomyosarcoma is a pediatric disease specified by the recurrent chromosome translocations t(2;13) and t(1;13). These translocations result in the formation of the PAX3-FKHR and PAX7-FKHR fusion genes, which are thought to play a causal role in the genesis of this disease. Although PAX3-F...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Lagutina, Irina, Conway, Simon J., Sublett, Jack, Grosveld, Gerard C.
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 2002
Matèries:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139793/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12242297/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.20.7204-7216.2002
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