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cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene

Alveolar rhabdomyosarcoma is an aggressive pediatric cancer of striated muscle characterized in 60% of cases by a t(2;13)(q35;q14). This results in the fusion of PAX3, a developmental transcription factor required for limb myogenesis, with FKHR, a member of the forkhead family of transcription facto...

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Autori principali: Khan, Javed, Bittner, Michael L., Saal, Lao H., Teichmann, Ulrike, Azorsa, David O., Gooden, Gerald C., Pavan, William J., Trent, Jeffrey M., Meltzer, Paul S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC23936/
https://ncbi.nlm.nih.gov/pubmed/10557309
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