Cyclodextrins sequester neuroactive steroids and differentiate mechanisms that rate limit steroid actions

BACKGROUND AND PURPOSE: Neuroactive steroids are potent modulators of GABA(A) receptors and are thus of interest for their sedative, anxiolytic, anticonvulsant and anaesthetic properties. Cyclodextrins may be useful tools to manipulate neuroactive effects of steroids on GABA(A) receptors because cyc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Shu, H-J, Zeng, C-M, Wang, C, Covey, D F, Zorumski, C F, Mennerick, S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2006
Gaiak:
Research Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042897/
https://ncbi.nlm.nih.gov/pubmed/17160009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706973
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