The pharmacokinetics of methadone in healthy subjects and opiate users

Aims There is some evidence that monitoring methadone plasma concentration may be of benefit in dosage adjustment during methadone maintenance therapy for heroin (opiate) dependence. However, the kinetics of oral methadone are incompletely characterized. We attempted to describe the latter using a p...

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Autores principales: Wolff, K., Rostami-Hodjegan, A., Shires, S., Hay, A. W. M., Feely, M., Calvert, R., Raistrick, D., Tucker, G. T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1997
Materias:
Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042854/
https://ncbi.nlm.nih.gov/pubmed/9354306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1997.t01-1-00591.x
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