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The pharmacokinetics of methadone in healthy subjects and opiate users

Aims There is some evidence that monitoring methadone plasma concentration may be of benefit in dosage adjustment during methadone maintenance therapy for heroin (opiate) dependence. However, the kinetics of oral methadone are incompletely characterized. We attempted to describe the latter using a p...

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Bibliografiske detaljer
Main Authors: Wolff, K., Rostami-Hodjegan, A., Shires, S., Hay, A. W. M., Feely, M., Calvert, R., Raistrick, D., Tucker, G. T.
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042854/
https://ncbi.nlm.nih.gov/pubmed/9354306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1997.t01-1-00591.x
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