Population Pharmacokinetics and Pharmacokinetic-Pharmacodynamic Relationships of Methadone in a Sample of Iranian (Mazandarani) Opiate Users Undergoing Methadone Maintenance Treatment

Objective: To investigate the pharmacokinetics (PK) and PK- pharmacodynamic (PD) relationship of methadone in a cohort of outpatients undergoing methadone maintenance treatment (MMT). Methods: Sixty male patients undergoing MMT with a mean ±SD methadone daily dosage of 58 ± 34 mg were enrolled in th...

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Bibliographische Detailangaben
Hauptverfasser: Shiran, Mohammad-Reza, Hosseinzadeh, Rasa, Hamidikenari, Abolhassan, Zarghami, Mehran, Lamsehchi, Nargess, Rafati, Mohammad-Reza
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mazandaran University of Medical Sciences 2011
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939965/
https://ncbi.nlm.nih.gov/pubmed/24644447
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