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Differences in orbitofrontal activation during decision-making between methadone-maintained opiate users, heroin users and healthy volunteers

OBJECTIVE: Previously, we reported that opiate users enrolled in methadone treatment made ‘risky’ choices on a decision-making task following a loss of points compared with heroin users and healthy volunteers. One possible explanation for this behaviour is that methadone users were less sensitive to...

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Detalhes bibliográficos
Main Authors: Ersche, Karen D., Fletcher, Paul C., Roiser, Jonathan P., Fryer, Tim D., London, Mervyn, Robbins, Trevor W., Sahakian, Barbara J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1903380/
https://ncbi.nlm.nih.gov/pubmed/16953385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-006-0515-z
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