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A novel mutant variant of the CYP2D6 gene (CYP2D6 17) common in a black African population: association with diminished debrisoquine hydroxylase activity

1The debrisoquine hydroxylase (CYP2D6) is polymorphically distributed. Not only are there differences in the proportions of extensive metabolisers to poor metabolisers in various ethnic groups, but there are also pronounced variations in the metabolic capacity among those classified as extensive met...

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Detalhes bibliográficos
Main Authors: MASIMIREMBWA, COLLEN, PERSSON, IRENE, BERTILSSON, LEIF, HASLER, JULIA, INGELMAN-SUNDBERG, MAGNUS
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042718/
https://ncbi.nlm.nih.gov/pubmed/8971426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1996.00489.x
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