Lack of effect of chloroquine on the debrisoquine (CYP2D6) and S-mephenytoin (CYP2C19) hydroxylation phenotypes

The effects of chloroquine (CHQ) on debrisoquine hydroxylase (CYP2D6) and S-mephenytoin hydroxylase (CYP2C19) were assessed in 11 black Zimbabwean and 12 white Swedish healthy volunteers. The activity of CYP2D6 was measured as the urinary debrisoquine to 4-hydroxydebrisoquine metabolic ratio and tha...

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Detalhes bibliográficos
Main Authors: MASIMIREMBWA, COLLEN M., GUSTAFSSON, LARS L., DAHL, MARJA-LIISA, ABDI, YAKOUB ADEN, HASLER, JULIA A.
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042586/
https://ncbi.nlm.nih.gov/pubmed/8730982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1996.30713.x
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