Lack of effect of chloroquine on the debrisoquine (CYP2D6) and S-mephenytoin (CYP2C19) hydroxylation phenotypes

The effects of chloroquine (CHQ) on debrisoquine hydroxylase (CYP2D6) and S-mephenytoin hydroxylase (CYP2C19) were assessed in 11 black Zimbabwean and 12 white Swedish healthy volunteers. The activity of CYP2D6 was measured as the urinary debrisoquine to 4-hydroxydebrisoquine metabolic ratio and tha...

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Hlavní autoři: MASIMIREMBWA, COLLEN M., GUSTAFSSON, LARS L., DAHL, MARJA-LIISA, ABDI, YAKOUB ADEN, HASLER, JULIA A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1996
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042586/
https://ncbi.nlm.nih.gov/pubmed/8730982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1996.30713.x
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