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Lack of relationship between glibenclamide metabolism and debrisoquine or mephenytoin hydroxylation phenotypes.

The pharmacokinetics of a single oral dose of 1.75 mg glibenclamide were studied in 15 healthy Caucasians including five poor metabolisers of debrisoquine and five poor metabolisers of S-mephenytoin. Plasma glibenclamide concentrations and the urinary concentrations of trans-4- and cis-3-hydroxyglib...

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Detaylı Bibliyografya
Asıl Yazarlar: Dahl-Puustinen, M L, Alm, C, Bertilsson, L, Christenson, I, Ostman, J, Thunberg, E, Wikström, I
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1990
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1368152/
https://ncbi.nlm.nih.gov/pubmed/2121211
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