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In vivo inhibition of CYP2C19 but not CYP2D6 by fluvoxamine
Studies were performed in eight healthy extensive metabolizers of mephenytoin and debrisoquine to determine the effect of fluvoxamine on the activities of S-mephenytoin 4′-hydroxylase (CYP2C19) and metoprolol α-hydroxylase (CYP2D6). Therapeutic dosing with fluvoxamine (100 mg day(−1)) for 2 weeks ca...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2042705/ https://ncbi.nlm.nih.gov/pubmed/8904628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1996.45319.x |
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