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Analysis of the dihydropyrimidine dehydrogenase polymorphism in a British population

Subjects with low or absent dihydropyrimidine dehydrogenase activity (DPD) are at risk of excessive toxicity or death when undergoing fluoropyrimidine chemotherapy. The DPD polymorphism has not been well characterized in the general population and the frequency of the enzyme deficiency is not known....

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Détails bibliographiques
Auteurs principaux: McMURROUGH, J., McLEOD, H. L.
Format: Artigo
Langue:Inglês
Publié: 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042607/
https://ncbi.nlm.nih.gov/pubmed/8735686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1996.34212.x
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