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Dihydropyrimidine dehydrogenase pharmacogenetics in Caucasian subjects
AIMS: Dihydropyrimidine dehydrogenase (DPD) catalyses the reduction of pyrimidines, including the anticancer agent 5-fluorouracil (5FU). Impaired 5FU degradation, through low DPD activity, has led to severe, life-threatening or fatal toxicity after administration of 5FU. Complete DPD deficiency is a...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Blackwell Science Inc
1998
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1873668/ https://ncbi.nlm.nih.gov/pubmed/9723824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.00751.x |
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