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Analysis of the dihydropyrimidine dehydrogenase polymorphism in a British population
Subjects with low or absent dihydropyrimidine dehydrogenase activity (DPD) are at risk of excessive toxicity or death when undergoing fluoropyrimidine chemotherapy. The DPD polymorphism has not been well characterized in the general population and the frequency of the enzyme deficiency is not known....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2042607/ https://ncbi.nlm.nih.gov/pubmed/8735686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1996.34212.x |
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