Small-Molecule Inhibition of HIV pre-mRNA Splicing as a Novel Antiretroviral Therapy to Overcome Drug Resistance

The development of multidrug-resistant viruses compromises antiretroviral therapy efficacy and limits therapeutic options. Therefore, it is an ongoing task to identify new targets for antiretroviral therapy and to develop new drugs. Here, we show that an indole derivative (IDC16) that interferes wit...

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Detalhes bibliográficos
Main Authors: Bakkour, Nadia, Lin, Yea-Lih, Maire, Sophie, Ayadi, Lilia, Mahuteau-Betzer, Florence, Nguyen, Chi Hung, Mettling, Clément, Portales, Pierre, Grierson, David, Chabot, Benoit, Jeanteur, Philippe, Branlant, Christiane, Corbeau, Pierre, Tazi, Jamal
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042022/
https://ncbi.nlm.nih.gov/pubmed/17967062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0030159
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