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Cell surface CCR5 density determines the postentry efficiency of R5 HIV-1 infection
We have recently reported that the mean number of CCR5 coreceptors at the surface of CD4(+) T cells (CCR5 density) correlates with viral load and disease progression in HIV-1-infected persons. Here, we definitively establish that CCR5 density determines the level of virus production and identify the...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137761/ https://ncbi.nlm.nih.gov/pubmed/12434015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.242134499 |
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